Characterisation and Antimicrobial Potential of Actinobacteria Isolated from Momela Soda Lakes, Tanzania

Extreme environments such as soda lakes are potential sources of microbes with biotechnological applications in different sectors. This study aimed at isolation, characterization and investigation antibacterial actinobacteria from Momela Soda Lakes, Arusha National Park Tanzania. One hundred twenty (120) isolates were recovered soil water samples using the dilution plate technique. The morphologically biochemically characterized, further, screened for antimicrobial activity by disc diffusion method well micro Cytotoxic effects determined brine shrimp lethality test. Results showed that, all 120 Gram-positive rod-coccus shaped. Forty-four out them against Staphylococcus aureus Escherichia coli. Streptomyces (101TI) Dietzia (56BI) strains exhibited exceptionally higher compared to rest inhibition zones 16.25 21.00 mm, respectively. These two toxic shrimp-larvae. Microbacterium (5LI), Hoyosella (113BI), (62BI), (117SI), (37SI) (3BI) had low cytotoxic activities. therefore revealed that Lakes harbour potential.
 Keywords: Actinobacteria; activity; extremophiles;